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Upf1p Control of Nonsense mRNA Translation Is Regulated by Nmd2p and Upf3p

Upf1p, Nmd2p, and Upf3p regulate the degradation of yeast mRNAs that contain premature translation termination codons. These proteins also appear to regulate the fidelity of termination, allowing translational suppression in their absence. Here, we have devised a novel quantitative assay for transla...

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Bibliographische Detailangaben
Hauptverfasser: Maderazo, Alan B., He, Feng, Mangus, David A., Jacobson, Allan
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2000
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC85857/
https://ncbi.nlm.nih.gov/pubmed/10848586
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