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Upf1p Control of Nonsense mRNA Translation Is Regulated by Nmd2p and Upf3p

Upf1p, Nmd2p, and Upf3p regulate the degradation of yeast mRNAs that contain premature translation termination codons. These proteins also appear to regulate the fidelity of termination, allowing translational suppression in their absence. Here, we have devised a novel quantitative assay for transla...

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Hlavní autoři: Maderazo, Alan B., He, Feng, Mangus, David A., Jacobson, Allan
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2000
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC85857/
https://ncbi.nlm.nih.gov/pubmed/10848586
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