Characterization of a CREB Gain-of-Function Mutant with Constitutive Transcriptional Activity In Vivo
The cyclic AMP (cAMP)-responsive factor CREB promotes cellular gene expression, following its phosphorylation at Ser133, via recruitment of the coactivator paralogs CREB-binding protein (CBP) and p300. CBP and p300, in turn, appear to mediate target gene induction via their association with RNA poly...
Guardat en:
| Publicat a: | Mol Cell Biol |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Taylor & Francis
2000
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85799/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10825195/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.12.4320-4327.2000 |
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