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IκB Kinase α (IKKα) Regulation of IKKβ Kinase Activity

Two related kinases, IκB kinase α (IKKα) and IKKβ, phosphorylate the IκB proteins, leading to their degradation and the subsequent activation of gene expression by NF-κB. IKKβ has a much higher level of kinase activity for the IκB proteins than does IKKα and is more critical than IKKα in modulating...

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Detalles Bibliográficos
Main Authors: Yamamoto, Yumi, Yin, Min-Jean, Gaynor, Richard B.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2000
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC85658/
https://ncbi.nlm.nih.gov/pubmed/10779355
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