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Role of Oxidative Phosphorylation in Bax Toxicity

The Bcl-2-related protein Bax is toxic when expressed either in yeast or in mammalian cells. Although the mechanism of this toxicity is unknown, it appears to be similar in both cell types and dependent on the localization of Bax to the outer mitochondrial membrane. To investigate the role of mitoch...

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Autori principali: Harris, Marian H., Vander Heiden, Matthew G., Kron, Stephen J., Thompson, Craig B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2000
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC85651/
https://ncbi.nlm.nih.gov/pubmed/10779348
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