Ku Recruits the XRCC4-Ligase IV Complex to DNA Ends
Genetic experiments have determined that Ku, XRCC4, and ligase IV are required for repair of double-strand breaks by the end-joining pathway. The last two factors form a tight complex in cells. However, ligase IV is only one of three known mammalian ligases and is intrinsically the least active in i...
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| Publicado no: | Mol Cell Biol |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85565/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10757784/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.9.2996-3003.2000 |
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