Ku Recruits the XRCC4-Ligase IV Complex to DNA Ends

Genetic experiments have determined that Ku, XRCC4, and ligase IV are required for repair of double-strand breaks by the end-joining pathway. The last two factors form a tight complex in cells. However, ligase IV is only one of three known mammalian ligases and is intrinsically the least active in i...

詳細記述

書誌詳細

出版年:	Mol Cell Biol
主要な著者:	Nick McElhinny, Stephanie A., Snowden, Carey M., McCarville, Joseph, Ramsden, Dale A.
フォーマット:	Artigo
言語:	Inglês
出版事項:	Taylor & Francis 2000
主題:	DNA Dynamics and Chromosome Structure
オンライン･アクセス:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85565/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10757784/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.9.2996-3003.2000
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