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Human DNA polymerase mu (Pol µ) exhibits an unusual replication slippage ability at AAF lesion

We analyzed the ability of various cell extracts to extend a radiolabeled primer past an N-2-acetylaminofluorene (AAF) adduct located on a primed single-stranded template. When the 3′ end of the primer is located opposite the lesion, partially fractionated human primary fibroblast extracts efficient...

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Detalhes bibliográficos
Main Authors: Duvauchelle, Jean-Baptiste, Blanco, Luis, Fuchs, Robert P. P., Cordonnier, Agnes M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC113843/
https://ncbi.nlm.nih.gov/pubmed/11972346
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