Two Sensitive PCR-Based Methods for Detection of Hepatitis B Virus Variants Associated with Reduced Susceptibility to Lamivudine

Two novel assays, a restriction fragment length polymorphism (RFLP) assay and an assay based on the 5′-nuclease activity of Taq DNA polymerase, were developed for screening viral variants in lamivudine-treated patients’ sera containing <1,000 copies of the hepatitis B virus (HBV) genome per ml. B...

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Detalhes bibliográficos
Main Authors: Allen, Marchelle I., Gauthier, Josee, DesLauriers, Manon, Bourne, Eric J., Carrick, Kevin M., Baldanti, Fausto, Ross, Lisa L., Lutz, Michael W., Condreay, Lynn D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
Assuntos:
Virology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC85560/
https://ncbi.nlm.nih.gov/pubmed/10488202
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