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Recruitment of a Basal Polyadenylation Factor by the Upstream Sequence Element of the Human Lamin B2 Polyadenylation Signal

We have investigated how the upstream sequence element (USE) of the lamin B2 poly(A) signal mediates efficient 3′-end formation. In vitro analysis demonstrates that this USE increases both the efficiency of 3′-end cleavage and the processivity of poly(A) addition. Cross-linking using selectively lab...

詳細記述

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書誌詳細
主要な著者: Brackenridge, Simon, Proudfoot, Nicholas J.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2000
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC85481/
https://ncbi.nlm.nih.gov/pubmed/10733568
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