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Recruitment of a Basal Polyadenylation Factor by the Upstream Sequence Element of the Human Lamin B2 Polyadenylation Signal

We have investigated how the upstream sequence element (USE) of the lamin B2 poly(A) signal mediates efficient 3′-end formation. In vitro analysis demonstrates that this USE increases both the efficiency of 3′-end cleavage and the processivity of poly(A) addition. Cross-linking using selectively lab...

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Bibliografiske detaljer
Main Authors: Brackenridge, Simon, Proudfoot, Nicholas J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2000
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC85481/
https://ncbi.nlm.nih.gov/pubmed/10733568
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