Recruitment of a Basal Polyadenylation Factor by the Upstream Sequence Element of the Human Lamin B2 Polyadenylation Signal

We have investigated how the upstream sequence element (USE) of the lamin B2 poly(A) signal mediates efficient 3′-end formation. In vitro analysis demonstrates that this USE increases both the efficiency of 3′-end cleavage and the processivity of poly(A) addition. Cross-linking using selectively lab...

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Autores principales: Brackenridge, Simon, Proudfoot, Nicholas J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2000
Materias:
Gene Expression
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC85481/
https://ncbi.nlm.nih.gov/pubmed/10733568
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