DNA Interstrand Cross-Links Induce Futile Repair Synthesis in Mammalian Cell Extracts

DNA interstrand cross-links are induced by many carcinogens and anticancer drugs. It was previously shown that mammalian DNA excision repair nuclease makes dual incisions 5′ to the cross-linked base of a psoralen cross-link, generating a gap of 22 to 28 nucleotides adjacent to the cross-link. We wis...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Mu, David, Bessho, Tadayoshi, Nechev, Lubomir V., Chen, David J., Harris, Thomas M., Hearst, John E., Sancar, Aziz
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2000
Ämnen:
DNA Dynamics and Chromosome Structure
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC85433/
https://ncbi.nlm.nih.gov/pubmed/10713168
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk