DNA Interstrand Cross-Links Induce Futile Repair Synthesis in Mammalian Cell Extracts

DNA interstrand cross-links are induced by many carcinogens and anticancer drugs. It was previously shown that mammalian DNA excision repair nuclease makes dual incisions 5′ to the cross-linked base of a psoralen cross-link, generating a gap of 22 to 28 nucleotides adjacent to the cross-link. We wis...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Mu, David, Bessho, Tadayoshi, Nechev, Lubomir V., Chen, David J., Harris, Thomas M., Hearst, John E., Sancar, Aziz
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2000
Assuntos:	DNA Dynamics and Chromosome Structure
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85433/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10713168/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.7.2446-2454.2000
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