Nucleotide Excision Repair- and Polymerase η-Mediated Error-Prone Removal of Mitomycin C Interstrand Cross-Links

Interstrand cross-links (ICLs) make up a unique class of DNA lesions in which both strands of the double helix are covalently joined, precluding strand opening during replication and transcription. The repair of DNA ICLs has become a focus of study since ICLs are recognized as the main cytotoxic les...

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Autori principali: Zheng, Huyong, Wang, Xin, Warren, Amy J., Legerski, Randy J., Nairn, Rodney S., Hamilton, Joshua W., Li, Lei
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2003
Soggetti:
DNA Dynamics and Chromosome Structure
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC151552/
https://ncbi.nlm.nih.gov/pubmed/12509472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.2.754-761.2003
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