Nucleotide Excision Repair/TFIIH Helicases Rad3 and Ssl2 Inhibit Short-Sequence Recombination and Ty1 Retrotransposition by Similar Mechanisms

Eukaryotic genomes contain potentially unstable sequences whose rearrangement threatens genome structure and function. Here we show that certain mutant alleles of the nucleotide excision repair (NER)/TFIIH helicase genes RAD3 and SSL2 (RAD25) confer synthetic lethality and destabilize the Saccharomy...

Cijeli opis

Bibliografski detalji

Izdano u:	Mol Cell Biol
Glavni autori:	Lee, Bum-Soo, Bi, Liu, Garfinkel, David J., Bailis, Adam M.
Format:	Artigo
Jezik:	Inglês
Izdano:	Taylor & Francis 2000
Teme:	DNA Dynamics and Chromosome Structure
Online pristup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85430/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10713167/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.7.2436-2445.2000
Oznake:	Dodaj oznaku Bez oznaka, Budi prvi tko označuje ovaj zapis!