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Nucleotide Excision Repair/TFIIH Helicases Rad3 and Ssl2 Inhibit Short-Sequence Recombination and Ty1 Retrotransposition by Similar Mechanisms

Eukaryotic genomes contain potentially unstable sequences whose rearrangement threatens genome structure and function. Here we show that certain mutant alleles of the nucleotide excision repair (NER)/TFIIH helicase genes RAD3 and SSL2 (RAD25) confer synthetic lethality and destabilize the Saccharomy...

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Publicado en:Mol Cell Biol
Autores principales: Lee, Bum-Soo, Bi, Liu, Garfinkel, David J., Bailis, Adam M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2000
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85430/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10713167/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.7.2436-2445.2000
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