SKIP, a CBF1-Associated Protein, Interacts with the Ankyrin Repeat Domain of NotchIC To Facilitate NotchIC Function

Notch proteins are transmembrane receptors that mediate intercell communication and direct individual cell fate decisions. The activated intracellular form of Notch, NotchIC, translocates to the nucleus, where it targets the DNA binding protein CBF1. CBF1 mediates transcriptional repression through...

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Auteurs principaux: Zhou, Sifang, Fujimuro, Masahiro, Hsieh, James J.-D., Chen, Lin, Miyamoto, Alison, Weinmaster, Gerry, Hayward, S. Diane
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2000
Sujets:
Transcriptional Regulation
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC85419/
https://ncbi.nlm.nih.gov/pubmed/10713164
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