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The Epstein–Barr virus latency BamHI-Q promoter is positively regulated by STATs and Zta interference with JAK/STAT activation leads to loss of BamHI-Q promoter activity

In Epstein–Barr virus (EBV)-associated tumors in nonimmunocompromised patients, EBV gene expression is highly restricted. EBV-encoded nuclear antigen (EBNA)-1 is expressed, whereas the immunogenic and proliferative EBNAs are not. This pattern of EBNA expression is generated by usage of the BamHI-Q p...

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Bibliografiske detaljer
Main Authors: Chen, Honglin, Lee, Jae Myun, Wang, Yilong, Huang, Dolly P., Ambinder, Richard F., Hayward, S. Diane
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 1999
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC17784/
https://ncbi.nlm.nih.gov/pubmed/10430944
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