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SKIP, a CBF1-Associated Protein, Interacts with the Ankyrin Repeat Domain of NotchIC To Facilitate NotchIC Function

Notch proteins are transmembrane receptors that mediate intercell communication and direct individual cell fate decisions. The activated intracellular form of Notch, NotchIC, translocates to the nucleus, where it targets the DNA binding protein CBF1. CBF1 mediates transcriptional repression through...

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Publicat a:Mol Cell Biol
Autors principals: Zhou, Sifang, Fujimuro, Masahiro, Hsieh, James J.-D., Chen, Lin, Miyamoto, Alison, Weinmaster, Gerry, Hayward, S. Diane
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2000
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85419/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10713164/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.7.2400-2410.2000
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