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Inhibition of IκB Kinase and IκB Phosphorylation by 15-Deoxy-Δ(12,14)-Prostaglandin J(2) in Activated Murine Macrophages
Activation of the macrophage cell line RAW 264.7 with lipopolysaccharide (LPS) and gamma interferon (IFN-γ) induces the expression of gene products involved in host defense, among them type 2 nitric oxide synthase. Treatment of cells with 15-deoxy-Δ(12,14)-prostaglandin J(2) (15dPGJ(2)) inhibited th...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology
2000
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC85352/ https://ncbi.nlm.nih.gov/pubmed/10669746 |
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