Inhibition of IκB Kinase and IκB Phosphorylation by 15-Deoxy-Δ(12,14)-Prostaglandin J(2) in Activated Murine Macrophages

Activation of the macrophage cell line RAW 264.7 with lipopolysaccharide (LPS) and gamma interferon (IFN-γ) induces the expression of gene products involved in host defense, among them type 2 nitric oxide synthase. Treatment of cells with 15-deoxy-Δ(12,14)-prostaglandin J(2) (15dPGJ(2)) inhibited th...

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Detalhes bibliográficos
Main Authors: Castrillo, Antonio, Díaz-Guerra, María J. M., Hortelano, Sonsoles, Martín-Sanz, Paloma, Boscá, Lisardo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC85352/
https://ncbi.nlm.nih.gov/pubmed/10669746
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