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Tyrosine Phosphorylation Mediates Both Activation and Downmodulation of the Biological Activity of Vav

Vav works as a GDP/GTP exchange factor for Rac GTPases, thereby facilitating the transition of these proteins from the inactive (GDP-bound) into the active (GTP-bound) state. The stimulation of Vav exchange activity during cell signaling is mediated by tyrosine phosphorylation. To understand the rol...

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Xehetasun bibliografikoak
Egile Nagusiak: López-Lago, Miguel, Lee, Hyunmi, Cruz, Cristina, Movilla, Nieves, Bustelo, Xosé R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2000
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC85351/
https://ncbi.nlm.nih.gov/pubmed/10669745
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