Tyrosine Phosphorylation Mediates Both Activation and Downmodulation of the Biological Activity of Vav
Vav works as a GDP/GTP exchange factor for Rac GTPases, thereby facilitating the transition of these proteins from the inactive (GDP-bound) into the active (GTP-bound) state. The stimulation of Vav exchange activity during cell signaling is mediated by tyrosine phosphorylation. To understand the rol...
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| Yayımlandı: | Mol Cell Biol |
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| Asıl Yazarlar: | , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Taylor & Francis
2000
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85351/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10669745/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.5.1678-1691.2000 |
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