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Akt Suppresses Apoptosis by Stimulating the Transactivation Potential of the RelA/p65 Subunit of NF-κB

It is well established that cell survival signals stimulated by growth factors, cytokines, and oncoproteins are initiated by phosphoinositide 3-kinase (PI3K)- and Akt-dependent signal transduction pathways. Oncogenic Ras, an upstream activator of Akt, requires NF-κB to initiate transformation, at le...

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Bibliografske podrobnosti
izdano v:Mol Cell Biol
Principais autores: Madrid, Lee V., Wang, Cun-Yu, Guttridge, Denis C., Schottelius, Arndt J. G., Baldwin, Albert S., Mayo, Marty W.
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2000
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85346/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10669740/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.5.1626-1638.2000
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