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MdmX Protects p53 from Mdm2-Mediated Degradation

The p53 tumor suppressor protein is stabilized in response to cellular stress, resulting in activation of genes responsible for either cell cycle arrest or apoptosis. The cellular pathway for releasing normal cells from p53-dependent cell cycle arrest involves the Mdm2 protein. Recently, a p53-bindi...

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Bibliografische gegevens
Hoofdauteurs: Jackson, Mark W., Berberich, Steven J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2000
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC85217/
https://ncbi.nlm.nih.gov/pubmed/10629057
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