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MdmX Protects p53 from Mdm2-Mediated Degradation

The p53 tumor suppressor protein is stabilized in response to cellular stress, resulting in activation of genes responsible for either cell cycle arrest or apoptosis. The cellular pathway for releasing normal cells from p53-dependent cell cycle arrest involves the Mdm2 protein. Recently, a p53-bindi...

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Autors principals: Jackson, Mark W., Berberich, Steven J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC85217/
https://ncbi.nlm.nih.gov/pubmed/10629057
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