Triple-Helix Formation Induces Recombination in Mammalian Cells via a Nucleotide Excision Repair-Dependent Pathway

The ability to stimulate recombination in a site-specific manner in mammalian cells may provide a useful tool for gene knockout and a valuable strategy for gene therapy. We previously demonstrated that psoralen adducts targeted by triple-helix-forming oligonucleotides (TFOs) could induce recombinati...

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Bibliographic Details
Main Authors: Faruqi, A. Fawad, Datta, Hirock J., Carroll, Dana, Seidman, Michael M., Glazer, Peter M.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2000
Subjects:
DNA Dynamics and Chromosome Structure
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC85216/
https://ncbi.nlm.nih.gov/pubmed/10629056
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