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Normal Hematopoiesis and Inflammatory Responses Despite Discrete Signaling Defects in Gα15 Knockout Mice

Gα15 activates phospholipase Cβ in response to the greatest variety of agonist-stimulated heptahelical receptors among the four Gq class G-protein α subunits expressed in mammals. Gα15 is primarily expressed in hematopoietic cells in fetal and adult mice. We disrupted the Gα15 gene by homologous rec...

Cur síos iomlán

Sábháilte in:
Sonraí bibleagrafaíochta
Foilsithe in:Mol Cell Biol
Príomhchruthaitheoirí: Davignon, I., Catalina, M. D., Smith, D., Montgomery, J., Swantek, J., Croy, J., Siegelman, M., Wilkie, T. M.
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: Taylor & Francis 2000
Ábhair:
Rochtain ar líne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85196/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10629036/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.3.797-804.2000
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