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Engineering Mouse Chromosomes with Cre-loxP: Range, Efficiency, and Somatic Applications

Chromosomal rearrangements are important resources for genetic studies. Recently, a Cre-loxP-based method to introduce defined chromosomal rearrangements (deletions, duplications, and inversions) into the mouse genome (chromosome engineering) has been established. To explore the limits of this techn...

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Bibliografiset tiedot
Julkaisussa:Mol Cell Biol
Päätekijät: Zheng, Binhai, Sage, Marijke, Sheppeard, Elizabeth A., Jurecic, Vesna, Bradley, Allan
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Taylor & Francis 2000
Aiheet:
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85158/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10611243/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.2.648-655.2000
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