Engineering Mouse Chromosomes with Cre-loxP: Range, Efficiency, and Somatic Applications

Chromosomal rearrangements are important resources for genetic studies. Recently, a Cre-loxP-based method to introduce defined chromosomal rearrangements (deletions, duplications, and inversions) into the mouse genome (chromosome engineering) has been established. To explore the limits of this techn...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Zheng, Binhai, Sage, Marijke, Sheppeard, Elizabeth A., Jurecic, Vesna, Bradley, Allan
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2000
Assuntos:	DNA Dynamics and Chromosome Structure
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85158/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10611243/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.2.648-655.2000
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