p53 Deficiency Increases Transformation by v-Abl and Rescues the Ability of a C-Terminally Truncated v-Abl Mutant To Induce Pre-B Lymphoma In Vivo

Abelson murine leukemia virus (A-MuLV) is an acute transforming retrovirus that preferentially transforms early B-lineage cells both in vivo and in vitro. Its transforming protein, v-Abl, is a tyrosine kinase related to v-Src but containing an extended C-terminal domain. Many mutations affecting the...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Zou, Xiaoming, Cong, Feng, Coutts, Margaret, Cattoretti, Giorgio, Goff, Stephen P., Calame, Kathryn
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2000
Assuntos:	Cell Growth and Development
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85151/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10611241/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.2.628-633.2000
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