Wird geladen...

p53 Deficiency Increases Transformation by v-Abl and Rescues the Ability of a C-Terminally Truncated v-Abl Mutant To Induce Pre-B Lymphoma In Vivo

Abelson murine leukemia virus (A-MuLV) is an acute transforming retrovirus that preferentially transforms early B-lineage cells both in vivo and in vitro. Its transforming protein, v-Abl, is a tyrosine kinase related to v-Src but containing an extended C-terminal domain. Many mutations affecting the...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Zou, Xiaoming, Cong, Feng, Coutts, Margaret, Cattoretti, Giorgio, Goff, Stephen P., Calame, Kathryn
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2000
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC85151/
https://ncbi.nlm.nih.gov/pubmed/10611241
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!