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p53 Deficiency Increases Transformation by v-Abl and Rescues the Ability of a C-Terminally Truncated v-Abl Mutant To Induce Pre-B Lymphoma In Vivo

Abelson murine leukemia virus (A-MuLV) is an acute transforming retrovirus that preferentially transforms early B-lineage cells both in vivo and in vitro. Its transforming protein, v-Abl, is a tyrosine kinase related to v-Src but containing an extended C-terminal domain. Many mutations affecting the...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Zou, Xiaoming, Cong, Feng, Coutts, Margaret, Cattoretti, Giorgio, Goff, Stephen P., Calame, Kathryn
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2000
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC85151/
https://ncbi.nlm.nih.gov/pubmed/10611241
Tagiau: Ychwanegu Tag
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