A Double-Strand Break in a Chromosomal LINE Element Can Be Repaired by Gene Conversion with Various Endogenous LINE Elements in Mouse Cells

A double-strand break (DSB) in the mammalian genome has been shown to be a very potent signal for the cell to activate repair processes. Two different types of repair have been identified in mammalian cells. Broken ends can be rejoined with or without loss or addition of DNA or, alternatively, a hom...

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Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Tremblay, Annie, Jasin, Maria, Chartrand, Pierre
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 2000
Schlagworte:	DNA Dynamics and Chromosome Structure
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85044/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10594008/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.1.54-60.2000
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