A Double-Strand Break in a Chromosomal LINE Element Can Be Repaired by Gene Conversion with Various Endogenous LINE Elements in Mouse Cells

A double-strand break (DSB) in the mammalian genome has been shown to be a very potent signal for the cell to activate repair processes. Two different types of repair have been identified in mammalian cells. Broken ends can be rejoined with or without loss or addition of DNA or, alternatively, a hom...

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Detalles Bibliográficos

Publicado en:	Mol Cell Biol
Autores principales:	Tremblay, Annie, Jasin, Maria, Chartrand, Pierre
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Taylor & Francis 2000
Materias:	DNA Dynamics and Chromosome Structure
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85044/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10594008/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.1.54-60.2000
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