Multiple Pathways for Repair of DNA Double-Strand Breaks in Mammalian Chromosomes
To study repair of DNA double-strand breaks (DSBs) in mammalian chromosomes, we designed DNA substrates containing a thymidine kinase (TK) gene disrupted by the 18-bp recognition site for yeast endonuclease I-SceI. Some substrates also contained a second defective TK gene sequence to serve as a gene...
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| Publicado no: | Mol Cell Biol |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84924/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10567560/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.12.8353 |
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