Multiple Pathways for Repair of DNA Double-Strand Breaks in Mammalian Chromosomes

To study repair of DNA double-strand breaks (DSBs) in mammalian chromosomes, we designed DNA substrates containing a thymidine kinase (TK) gene disrupted by the 18-bp recognition site for yeast endonuclease I-SceI. Some substrates also contained a second defective TK gene sequence to serve as a gene...

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Pubblicato in:	Mol Cell Biol
Autori principali:	Lin, Yunfu, Lukacsovich, Tamas, Waldman, Alan S.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 1999
Soggetti:	DNA Dynamics and Chromosome Structure
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84924/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10567560/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.12.8353
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