LAT Is Required for Tyrosine Phosphorylation of Phospholipase Cγ2 and Platelet Activation by the Collagen Receptor GPVI

In the present study, we have addressed the role of the linker for activation of T cells (LAT) in the regulation of phospholipase Cγ2 (PLCγ2) by the platelet collagen receptor glycoprotein VI (GPVI). LAT is tyrosine phosphorylated in human platelets heavily in response to collagen, collagen-related...

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Detalhes bibliográficos
Main Authors: Pasquet, Jean-Max, Gross, Barbara, Quek, Lynn, Asazuma, Naoki, Zhang, Weiguo, Sommers, Connie L., Schweighoffer, Edina, Tybulewicz, Victor, Judd, Barbara, Lee, Jong Ran, Koretzky, Gary, Love, Paul E., Samelson, Lawrence E., Watson, Steve P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC84916/
https://ncbi.nlm.nih.gov/pubmed/10567557
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