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LAT Is Required for Tyrosine Phosphorylation of Phospholipase Cγ2 and Platelet Activation by the Collagen Receptor GPVI

In the present study, we have addressed the role of the linker for activation of T cells (LAT) in the regulation of phospholipase Cγ2 (PLCγ2) by the platelet collagen receptor glycoprotein VI (GPVI). LAT is tyrosine phosphorylated in human platelets heavily in response to collagen, collagen-related...

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Autores principales: Pasquet, Jean-Max, Gross, Barbara, Quek, Lynn, Asazuma, Naoki, Zhang, Weiguo, Sommers, Connie L., Schweighoffer, Edina, Tybulewicz, Victor, Judd, Barbara, Lee, Jong Ran, Koretzky, Gary, Love, Paul E., Samelson, Lawrence E., Watson, Steve P.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 1999
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC84916/
https://ncbi.nlm.nih.gov/pubmed/10567557
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