Identification of a Portable Repression Domain and an E1A-Responsive Activation Domain in Pax4: a Possible Role of Pax4 as a Transcriptional Repressor in the Pancreas

Pax4 is a paired-domain (PD)-containing transcription factor which plays a crucial role in pancreatic β/δ-cell development. In this study, we characterized the DNA-binding and transactivation properties of mouse Pax4. Repetitive rounds of PCR-based selection led to identification of the optimal DNA-...

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Detalles Bibliográficos

Publicado en:	Mol Cell Biol
Autores principales:	Fujitani, Yoshio, Kajimoto, Yoshitaka, Yasuda, Tetsuyuki, Matsuoka, Taka-Aki, Kaneto, Hideaki, Umayahara, Yutaka, Fujita, Noriko, Watada, Hirotaka, Miyazaki, Jun-Ichi, Yamasaki, Yoshimitsu, Hori, Masatsugu
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Taylor & Francis 1999
Materias:	Transcriptional Regulation
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84912/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10567553/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.12.8281
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