Identification of a Portable Repression Domain and an E1A-Responsive Activation Domain in Pax4: a Possible Role of Pax4 as a Transcriptional Repressor in the Pancreas

Pax4 is a paired-domain (PD)-containing transcription factor which plays a crucial role in pancreatic β/δ-cell development. In this study, we characterized the DNA-binding and transactivation properties of mouse Pax4. Repetitive rounds of PCR-based selection led to identification of the optimal DNA-...

Full description

Saved in:
Bibliographic Details
Main Authors: Fujitani, Yoshio, Kajimoto, Yoshitaka, Yasuda, Tetsuyuki, Matsuoka, Taka-Aki, Kaneto, Hideaki, Umayahara, Yutaka, Fujita, Noriko, Watada, Hirotaka, Miyazaki, Jun-Ichi, Yamasaki, Yoshimitsu, Hori, Masatsugu
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1999
Subjects:
Transcriptional Regulation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC84912/
https://ncbi.nlm.nih.gov/pubmed/10567553
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items