Identification of a Portable Repression Domain and an E1A-Responsive Activation Domain in Pax4: a Possible Role of Pax4 as a Transcriptional Repressor in the Pancreas

Pax4 is a paired-domain (PD)-containing transcription factor which plays a crucial role in pancreatic β/δ-cell development. In this study, we characterized the DNA-binding and transactivation properties of mouse Pax4. Repetitive rounds of PCR-based selection led to identification of the optimal DNA-...

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Detalhes bibliográficos
Main Authors: Fujitani, Yoshio, Kajimoto, Yoshitaka, Yasuda, Tetsuyuki, Matsuoka, Taka-Aki, Kaneto, Hideaki, Umayahara, Yutaka, Fujita, Noriko, Watada, Hirotaka, Miyazaki, Jun-Ichi, Yamasaki, Yoshimitsu, Hori, Masatsugu
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
Assuntos:
Transcriptional Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC84912/
https://ncbi.nlm.nih.gov/pubmed/10567553
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