Evidence for Substrate-Specific Requirement of the Splicing Factor U2AF(35) and for Its Function after Polypyrimidine Tract Recognition by U2AF(65)
U2 snRNP auxiliary factor (U2AF) promotes U2 snRNP binding to pre-mRNAs and consists of two subunits of 65 and 35 kDa, U2AF(65) and U2AF(35). U2AF(65) binds to the polypyrimidine (Py) tract upstream from the 3′ splice site and plays a key role in assisting U2 snRNP recruitment. It has been proposed...
Guardat en:
| Publicat a: | Mol Cell Biol |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Taylor & Francis
1999
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84910/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10567551/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.12.8263 |
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