Dissection of the LXXLL Nuclear Receptor-Coactivator Interaction Motif Using Combinatorial Peptide Libraries: Discovery of Peptide Antagonists of Estrogen Receptors α and β
Recruitment of transcriptional coactivators following ligand activation is a critical step in nuclear receptor-mediated target gene expression. Upon binding an agonist, the receptor undergoes a conformational change which facilitates the formation of a specific coactivator binding pocket within the...
Zapisane w:
| Wydane w: | Mol Cell Biol |
|---|---|
| Główni autorzy: | , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Taylor & Francis
1999
|
| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84907/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10567548/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.12.8226 |
| Etykiety: |
Nie ma etykietki, Dołącz pierwszą etykiete!
|
