Evidence for a Protein Mutator in Yeast: Role of the Hsp70-Related Chaperone Ssb in Formation, Stability, and Toxicity of the [PSI] Prion

Propagation of the yeast protein-based non-Mendelian element [PSI], a prion-like form of the release factor Sup35, was shown to be regulated by the interplay between chaperone proteins Hsp104 and Hsp70. While overproduction of Hsp104 protein cures cells of [PSI], overproduction of the Ssa1 protein o...

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Publié dans:	Mol Cell Biol
Auteurs principaux:	Chernoff, Yury O., Newnam, Gary P., Kumar, Jaijit, Allen, Kim, Zink, Amy D.
Format:	Artigo
Langue:	Inglês
Publié:	Taylor & Francis 1999
Sujets:	Gene Expression
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84895/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10567536/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.12.8103
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