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Evidence for a Protein Mutator in Yeast: Role of the Hsp70-Related Chaperone Ssb in Formation, Stability, and Toxicity of the [PSI] Prion

Propagation of the yeast protein-based non-Mendelian element [PSI], a prion-like form of the release factor Sup35, was shown to be regulated by the interplay between chaperone proteins Hsp104 and Hsp70. While overproduction of Hsp104 protein cures cells of [PSI], overproduction of the Ssa1 protein o...

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Hlavní autoři: Chernoff, Yury O., Newnam, Gary P., Kumar, Jaijit, Allen, Kim, Zink, Amy D.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 1999
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC84895/
https://ncbi.nlm.nih.gov/pubmed/10567536
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