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Characterization of a Vacuolar Pyrophosphatase in Trypanosoma brucei and Its Localization to Acidocalcisomes

Inorganic pyrophosphate promoted the acidification of an intracellular compartment in permeabilized procyclic trypomastigotes of Trypanosoma brucei, as measured by acridine orange uptake. The proton gradient generated by pyrophosphate was collapsed by addition of nigericin or NH(4)Cl. Pyrophosphate-...

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Pubblicato in:Mol Cell Biol
Autori principali: Rodrigues, Claudia O., Scott, David A., Docampo, Roberto
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 1999
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84816/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10523660/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.11.7712
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