p57(Kip2) Stabilizes the MyoD Protein by Inhibiting Cyclin E-Cdk2 Kinase Activity in Growing Myoblasts

We show that expression of p57(Kip2), a potent tight-binding inhibitor of several G(1) cyclin–cyclin-dependent kinase (Cdk) complexes, increases markedly during C2C12 myoblast differentiation. We examined the effect of p57(Kip2) on the activity of the transcription factor MyoD. In transient transfec...

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Detalles Bibliográficos

Publicado en:	Mol Cell Biol
Autores principales:	Reynaud, Emmanuel G., Pelpel, Karine, Guillier, Martine, Leibovitch, Marie Pierre, Leibovitch, Serge A.
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Taylor & Francis 1999
Materias:	Cell Growth and Development
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84790/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10523650/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.11.7621
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