p57(Kip2) Stabilizes the MyoD Protein by Inhibiting Cyclin E-Cdk2 Kinase Activity in Growing Myoblasts
We show that expression of p57(Kip2), a potent tight-binding inhibitor of several G(1) cyclin–cyclin-dependent kinase (Cdk) complexes, increases markedly during C2C12 myoblast differentiation. We examined the effect of p57(Kip2) on the activity of the transcription factor MyoD. In transient transfec...
Shranjeno v:
| izdano v: | Mol Cell Biol |
|---|---|
| Principais autores: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Taylor & Francis
1999
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84790/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10523650/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.11.7621 |
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