Functional Independence and Interdependence of the Src Homology Domains of Phospholipase C-γ1 in B-Cell Receptor Signal Transduction

B-cell receptor (BCR)-induced activation of phospholipase C-γ1 (PLCγ1) and PLCγ2 is crucial for B-cell function. While several signaling molecules have been implicated in PLCγ activation, the mechanism coupling PLCγ to the BCR remains undefined. The role of PLCγ1 SH2 and SH3 domains at different ste...

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Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: DeBell, Karen E., Stoica, Bogdan A., Verí, Maria-Concetta, Di Baldassarre, Angela, Miscia, Sebastiano, Graham, Laurie J., Rellahan, Barbara L., Ishiai, Masamichi, Kurosaki, Tomohiro, Bonvini, Ezio
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 1999
Ämnen:
Cell Growth and Development
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC84732/
https://ncbi.nlm.nih.gov/pubmed/10523627
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